https://www.haereframedhcp.com/ 2026-04-29 https://www.haereframedhcp.com/wp-content/uploads/2026/02/haereframed-logo.png HAEReframed logo. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-home-desktop-1024x730.png Image of person screaming composed of HAE treatment items, text bubbles, and sticky notes. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-home-mobile.png Image of person screaming composed of HAE treatment items, text bubbles, and sticky notes. https://www.haereframedhcp.com/wp-content/uploads/2026/03/percentage-circle-80.svg Approximately 80%. https://www.haereframedhcp.com/wp-content/uploads/2026/03/percentage-orange-57.png 57%. https://www.haereframedhcp.com/wp-content/uploads/2026/03/percentage-teal-80.png 80%. https://www.haereframedhcp.com/wp-content/uploads/2026/03/intellia-logo.svg Intellia Therapeutics logo. https://www.haereframedhcp.com/site-map 2026-04-29 https://www.haereframedhcp.com/wp-content/uploads/2026/02/haereframed-logo.png HAEReframed logo. https://www.haereframedhcp.com/wp-content/uploads/2026/03/intellia-logo.svg Intellia Therapeutics logo. https://www.haereframedhcp.com/hereditary-angioedema-attacks 2026-04-29 https://www.haereframedhcp.com/wp-content/uploads/2026/02/haereframed-logo.png HAEReframed logo. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-canvas-desktop-1.png Image composed of HAE treatment items and text bubbles and sticky notes that say, I feel anxious and sad, Sorry I'm not coming. I'm swelling, and I'm in pain. I need help. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-canvas-mobile.png Image composed of HAE treatment items and text bubbles and sticky notes that say, I feel anxious and sad, Sorry I'm not coming. I'm swelling, and I'm in pain. I need help. https://www.haereframedhcp.com/wp-content/uploads/2026/03/percentage-orange-circle-80.svg Approximately 80%. https://www.haereframedhcp.com/wp-content/uploads/2026/03/percentage-teal-68.png 68%. https://www.haereframedhcp.com/wp-content/uploads/2026/03/hcp-life-disrupted-barChart-desktop1.svg A bar chart demonstrating that HCPs prioritize attack impact when evaluating if a patient's disease is well managed and their daily life normalized. https://www.haereframedhcp.com/wp-content/uploads/2026/03/hcp-life-disrupted-barChart-mobile1.svg A bar chart demonstrating that HCPs prioritize attack impact when evaluating if a patient's disease is well managed and their daily life normalized. https://www.haereframedhcp.com/wp-content/uploads/2026/03/hcp-life-disrupted-barChart-desktop.svg A bar chart showing results from a survey of patients with HAE. When asked about living a normal life, patients cited concerns around aspects of life-long disease management. https://www.haereframedhcp.com/wp-content/uploads/2026/03/hcp-life-disrupted-barChart-mobile.svg A bar chart showing results from a survey of patients with HAE. When asked about living a normal life, patients cited concerns around aspects of life-long disease management. https://www.haereframedhcp.com/wp-content/uploads/2026/03/intellia-logo.svg Intellia Therapeutics logo. https://www.haereframedhcp.com/hereditary-angioedema-burden 2026-04-29 https://www.haereframedhcp.com/wp-content/uploads/2026/02/haereframed-logo.png HAEReframed logo. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-patient-portrait-desktop-1.png Image composed of HAE treatment items and text bubbles and sticky notes that say, Call doctor to renew prescription, and Explain HAE to new boss. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-patient-portrait-mobile.png Image composed of HAE treatment items and text bubbles and sticky notes that say, Call doctor to renew prescription, and Explain HAE to new boss. https://www.haereframedhcp.com/wp-content/uploads/2026/03/percentage-orange-69.svg 69%. https://www.haereframedhcp.com/wp-content/uploads/2026/03/percentage-teal-28.svg 28%. https://www.haereframedhcp.com/wp-content/uploads/2026/03/percentage-orange-80-150x150.png 80%. https://www.haereframedhcp.com/wp-content/uploads/2026/04/Web_Text-Bubble_v4-1.png An illustration of a text message showing the message, Why was my renewal denied? My coverage hasn't changed. https://www.haereframedhcp.com/wp-content/uploads/2026/02/hcp-pink-stickynote.png An illustration of a handwritten note saying, I'm so tired of planning my entire life around this disease. https://www.haereframedhcp.com/wp-content/uploads/2026/03/intellia-logo.svg Intellia Therapeutics logo. https://www.haereframedhcp.com/hereditary-angioedema-science 2026-04-29 https://www.haereframedhcp.com/wp-content/uploads/2026/02/haereframed-logo.png HAEReframed logo. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-mod-desktop-1.png Image composed of HAE treatment items and text bubbles and sticky notes that say, New year—time to renew authorizations, Why is this so hard? Getting my meds shouldn't be a constant struggle, I need a letter of medical necessity for travel, and I’m in pain. I need help. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-mod-mobile.png Image composed of HAE treatment items and text bubbles and sticky notes that say, New year—time to renew authorizations, Why is this so hard? Getting my meds shouldn't be a constant struggle, I need a letter of medical necessity for travel, and I’m in pain. I need help. https://www.haereframedhcp.com/wp-content/uploads/2026/03/hcp-mod-angiodema.png A diagram illustrating the kallikrein-kinin system, a pathway that regulates swelling. It shows how the KLKB1 gene produces plasma prekallikrein, which ultimately leads to bradykinin production. C1-INH controls the kallikrein-kinin system, and C1-INH dysregulation causes the overproduction of bradykinin, which leads to HAE attacks. https://www.haereframedhcp.com/wp-content/uploads/2026/03/intellia-logo.svg Intellia Therapeutics logo. https://www.haereframedhcp.com/hereditary-angioedema-treatment-goals 2026-04-29 https://www.haereframedhcp.com/wp-content/uploads/2026/02/haereframed-logo.png HAEReframed logo. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-hae-care-desktop-1.png Image composed of HAE treatment items and text bubbles and sticky notes that say, Why is this so hard? Getting my meds shouldn’t be a constant struggle, Having a very sharp pain in my stomach, and Sorry, I’m not coming— I’m swelling. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-hae-care-mobile.png Image composed of HAE treatment items and text bubbles and sticky notes that say, Why is this so hard? Getting my meds shouldn’t be a constant struggle, Having a very sharp pain in my stomach, and Sorry, I’m not coming— I’m swelling. https://www.haereframedhcp.com/wp-content/uploads/2026/04/Patient-Brochure.png A patient brochure titled HAE Challenges Can Come in Waves. https://www.haereframedhcp.com/sign-up 2026-04-29 https://www.haereframedhcp.com/wp-content/uploads/2026/02/haereframed-logo.png HAEReframed logo. https://www.haereframedhcp.com/wp-content/uploads/2026/04/hcp-hae-thank-you-desktop.png Image composed of HAE treatment items, text bubbles, and sticky notes. https://www.haereframedhcp.com/wp-content/uploads/2026/04/HCP-SignUp-Mob.png Image composed of HAE treatment items, text bubbles, and sticky notes. https://www.haereframedhcp.com/wp-content/uploads/2026/03/intellia-logo.svg Intellia Therapeutics logo.